dc.contributor.advisor | Cakić, Milorad | |
dc.contributor.other | Nikolić, Goran S. | |
dc.contributor.other | Mitić, Žarko | |
dc.creator | Glišić, Slobodan Lj. | |
dc.date.accessioned | 2018-07-05T09:38:08Z | |
dc.date.available | 2018-07-05T09:38:08Z | |
dc.date.available | 2020-07-03T16:14:10Z | |
dc.date.issued | 2018-06-08 | |
dc.identifier.uri | https://nardus.mpn.gov.rs/handle/123456789/9588 | |
dc.identifier.uri | http://eteze.ni.ac.rs/application/showtheses?thesesId=5867 | |
dc.identifier.uri | https://fedorani.ni.ac.rs/fedora/get/o:1493/bdef:Content/download | |
dc.identifier.uri | http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533967766 | |
dc.description.abstract | The methods of the Cu and Co complexes synthesis with carboxymethyl
dextran (CMD) and dextran sulfate (DS), as well as the silver nanoparticles
(AgNPs) with Fumaria officinalis extract (E), and dextran derivatives have
been developed. Physicochemical, spectrophotometric and spectroscopic
investigations of divalent covalent cations Cu and Co complexes with CMD
and DS have shown that compounds of the following stoichiometry are
synthesized: Co(II)∙(CMD)2∙(H2O)2 and Co(II)∙DS∙(H2O)2, respectively,
Cu(II)∙(CMD)2∙(H2O)2 and Cu(II)∙DS∙(H2O)2 with a 4C1 conformation of α-
glucopyranose ring and two coordinated water molecules. CMD behaves as
a bidentate ligand with asymmetric chelating bonding, which may be the
reason for the formation of tetragonally deformed octahedral coordination.
Compounds with DS are predominantly ionic. Non-toxic, green synthesis
processes of AgNPs with CMD, DS and Fumaria officinalis extract have
been developed. The formation of AgNPs in all these cases has been
indicated by a color change of the reaction mixture as well as the existence
of surface plasmon resonance (SPR) band in the UV-Vis spectrum. The
spherical particle size was 20-60 nm (SEM), and the presence of AgNPs is
confirmed by the XRD and EDX method. Silver interactions with these
ligands are similar to those of the Co and Cu, except for AgNPs-E where the
functional groups with oxygen or nitrogen, such as (NH, (NH)C=O, CNO,
C-O-C and OH), play a role in the reduction Ag+ and stabilization of
AgNPs-E. A model of a general structure of AgNPs with CMD, DS and E is
proposed, which presupposes the existence of a thin organic substances coat
around AgNPs bounded by strong ionic or coordinative bonds with surface
silver ions. AgNPs-E, AgNPs-DS and AgNPs-CMD have shown
antimicrobial activity against analyzed microorganisms and can be used in
medicine, veterinary medicine, pharmacy, cosmetics, etc. | en |
dc.format | application/pdf | |
dc.language | sr | |
dc.publisher | Универзитет у Нишу, Технолошки факултет, Лесковац | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34012/RS// | |
dc.rights | openAccess | en |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Универзитет у Нишу | sr |
dc.subject | Biometali | sr |
dc.subject | Biometals | en |
dc.subject | spectroscopy | en |
dc.subject | koordinaciona
hemija | sr |
dc.subject | spektroskopija | sr |
dc.subject | polysaccharides | en |
dc.subject | complexes | en |
dc.subject | nanoparticles | en |
dc.subject | coordination chemistry | en |
dc.subject | polisaharidi | sr |
dc.subject | kompleksi | sr |
dc.subject | nanočestice | sr |
dc.title | Razvoj biokompleksa i nanočestica bioaktivnih metala stabilizovanih oligosaharidima | sr |
dc.type | doctoralThesis | en |
dc.rights.license | BY-NC-ND | |
dcterms.abstract | Цакић, Милорад; Николић, Горан С.; Митић, Жарко; Глишић, Слободан Љ.; Развој биокомплекса и наночестица биоактивних метала стабилизованих олигосахаридима; Развој биокомплекса и наночестица биоактивних метала стабилизованих олигосахаридима; | |
dc.identifier.fulltext | https://nardus.mpn.gov.rs/bitstream/id/54726/Disertacija.pdf | |
dc.identifier.fulltext | https://nardus.mpn.gov.rs/bitstream/id/54727/Glisic_Slobodan_Lj.pdf | |
dc.identifier.fulltext | http://nardus.mpn.gov.rs/bitstream/id/54726/Disertacija.pdf | |
dc.identifier.fulltext | http://nardus.mpn.gov.rs/bitstream/id/54727/Glisic_Slobodan_Lj.pdf | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_nardus_9588 | |