Nacionalni Repozitorijum Disertacija u Srbiji
    • English
    • Српски
    • Српски (Serbia)
  • Srpski (latinica) 
    • Engleski
    • Srpski (ćirilica)
    • Srpski (latinica)
  • Prijava
Pregled disertacije 
  •   NaRDuS - početna
  • Универзитет у Нишу
  • Технолошки факултет, Лесковац
  • Pregled disertacije
  •   NaRDuS - početna
  • Универзитет у Нишу
  • Технолошки факултет, Лесковац
  • Pregled disertacije
JavaScript is disabled for your browser. Some features of this site may not work without it.

Razvoj biokompleksa i nanočestica bioaktivnih metala stabilizovanih oligosaharidima

Thumbnail
2018
Disertacija.pdf (5.926Mb)
Glisic_Slobodan_Lj.pdf (6.575Mb)
Doktorand
Glišić, Slobodan Lj.
Mentor
Cakić, Milorad
Članovi komisije
Nikolić, Goran S.
Mitić, Žarko
Metapodaci
Prikaz svih podataka o disertaciji
Sažetak
The methods of the Cu and Co complexes synthesis with carboxymethyl dextran (CMD) and dextran sulfate (DS), as well as the silver nanoparticles (AgNPs) with Fumaria officinalis extract (E), and dextran derivatives have been developed. Physicochemical, spectrophotometric and spectroscopic investigations of divalent covalent cations Cu and Co complexes with CMD and DS have shown that compounds of the following stoichiometry are synthesized: Co(II)∙(CMD)2∙(H2O)2 and Co(II)∙DS∙(H2O)2, respectively, Cu(II)∙(CMD)2∙(H2O)2 and Cu(II)∙DS∙(H2O)2 with a 4C1 conformation of α- glucopyranose ring and two coordinated water molecules. CMD behaves as a bidentate ligand with asymmetric chelating bonding, which may be the reason for the formation of tetragonally deformed octahedral coordination. Compounds with DS are predominantly ionic. Non-toxic, green synthesis processes of AgNPs with CMD, DS and Fumaria officinalis extract have been developed. The formation of AgNPs in all these cases h...as been indicated by a color change of the reaction mixture as well as the existence of surface plasmon resonance (SPR) band in the UV-Vis spectrum. The spherical particle size was 20-60 nm (SEM), and the presence of AgNPs is confirmed by the XRD and EDX method. Silver interactions with these ligands are similar to those of the Co and Cu, except for AgNPs-E where the functional groups with oxygen or nitrogen, such as (NH, (NH)C=O, CNO, C-O-C and OH), play a role in the reduction Ag+ and stabilization of AgNPs-E. A model of a general structure of AgNPs with CMD, DS and E is proposed, which presupposes the existence of a thin organic substances coat around AgNPs bounded by strong ionic or coordinative bonds with surface silver ions. AgNPs-E, AgNPs-DS and AgNPs-CMD have shown antimicrobial activity against analyzed microorganisms and can be used in medicine, veterinary medicine, pharmacy, cosmetics, etc.

Fakultet:
Univerzitet u Nišu, Tehnološki fakultet, Leskovac
Datum odbrane:
08-06-2018
Projekti:
  • Biljni i sintetički bioaktivni proizvodi novije generacije (RS-34012)
Ključne reči:
Biometali / Biometals / spectroscopy / koordinaciona hemija / spektroskopija / polysaccharides / complexes / nanoparticles / coordination chemistry / polisaharidi / kompleksi / nanočestice
[ Google Scholar ]
Ostali linkovi:
http://eteze.ni.ac.rs/application/showtheses?thesesId=5867
http://nardus.mpn.gov.rs/handle/123456789/9588
https://fedorani.ni.ac.rs/fedora/get/o:1493/bdef:Content/download
http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533967766

DSpace software copyright © 2002-2015  DuraSpace
O NaRDuS portalu | Pošaljite zapažanja

OpenAIRERCUBRODOSTEMPUS
 

 

Pregled

Sve disertacijeUniverziteti i fakultetiDoktorandiMentoriČlanovi komisijaTemeFakultetDoktorandiMentoriČlanovi komisijaTeme

DSpace software copyright © 2002-2015  DuraSpace
O NaRDuS portalu | Pošaljite zapažanja

OpenAIRERCUBRODOSTEMPUS