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dc.contributor.advisorSokolović, Dušan
dc.contributor.otherKesić, Ljiljana
dc.contributor.otherPuškar, Tatjana
dc.creatorBošković, Mirjana V.
dc.date.accessioned2017-07-24T08:19:20Z
dc.date.available2017-07-24T08:19:20Z
dc.date.available2020-07-03T16:07:15Z
dc.date.issued2017-02-17
dc.identifier.urihttp://eteze.ni.ac.rs/application/showtheses?thesesId=5132
dc.identifier.urihttp://nardus.mpn.gov.rs/handle/123456789/8414
dc.identifier.urihttps://fedorani.ni.ac.rs/fedora/get/o:1378/bdef:Content/download
dc.identifier.urihttp://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533897110
dc.description.abstractTooth loss is a huge problem of the modern man. Use of new technologies and dental materials in the fabrication of fixed or mobile dental prosthetic appliances has an impact on the change of some of the biochemical parameters in the patient saliva. It is thought that to a degree, particular materials have an impact on the change of quality and quantity of saliva after their placement in the mouth cavity. The presence of metal ions as free ions in the mouth has got a large potential for the creation of factors that cause oxidative stress. A specially adverse effect has been observed with alloys used in the fabrication of fixed dental prosthetic appliances, since they cause allergic and hypersensitivity reactions in the mouth cavity. It has been shown that use of dental prosthetic appliances induces changes in the morphology and reduced motility of the cells, significant increase of oxidative stress, appearance of cytokines, and cell intoxication. With the placement of fixed dental prosthetic appliances patients tend to adapt to them much quicker than with mobile appliances, when the clinical signs of inflammation are much more common. With the application of fixed dental prosthetic appliances oxidative stress in the saliva is much less intense than with mobile appliances. A similar relationship has been found in the analysis of parameters of inflammation and markers of apoptosis in the saliva. Increased parameters of inflammation, oxidative stress, and apoptosis in the saliva of patients as the result of fixed dental prosthetic appliances, tend to normalize much more rapidly than with mobile appliances. The analyzed biochemical parameters normalize 30 days after the placement of fixed or mobile dental prosthetic appliances.en
dc.formatapplication/pdf
dc.languagesr
dc.publisherУниверзитет у Нишу, Медицински факултетsr
dc.rightsopenAccessen
dc.sourceУниверзитет у Нишуsr
dc.subjectpljuvaĉkasr
dc.subjectsalivaen
dc.subjectmobile dental prosthetic applianceen
dc.subjectfixed dental prosthetic applianceen
dc.subjectbiochemical parametars of inflammationen
dc.subjectmobilna stomatološka protetska nadoknadasr
dc.subjectfiskna stomatološka protetska nadoknadasr
dc.subjectbiohemijski parametri zapaljenjasr
dc.titlePraćenje biohemijskih parametara zapaljenja, oksidativnog stresa i apoptoze u pljuvačci pacijenata sa fiksnim i mobilnim stomatološkim protetskim nadoknadamasr
dc.typedoctoralThesis
dc.rights.licenseBY-NC-ND
dcterms.abstractСоколовић, Душан; Кесић, Љиљана; Пушкар, Татјана; Бошковић, Мирјана В.; Праћење биохемијских параметара запаљења, оксидативног стреса и апоптозе у пљувачци пацијената са фиксним и мобилним стоматолошким протетским надокнадама; Праћење биохемијских параметара запаљења, оксидативног стреса и апоптозе у пљувачци пацијената са фиксним и мобилним стоматолошким протетским надокнадама;
dc.identifier.fulltexthttp://nardus.mpn.gov.rs/bitstream/id/53183/Disertacija.pdf
dc.identifier.fulltexthttp://nardus.mpn.gov.rs/bitstream/id/53184/Boskovic_Mirjana_V.pdf


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