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Sinteza i biološka ispitivanja novih derivata žučnih kiselina

Synthesis and biological evaluation of new bile acid derivatives

dc.contributor.advisorSakač, Marija
dc.contributor.otherČanadi, Janoš
dc.contributor.otherSakač, Marija
dc.contributor.otherPopsavin, Mirjana
dc.contributor.otherMarkov, Siniša
dc.contributor.otherPoša, Mihalj
dc.creatorBjedov, Srđan
dc.date.accessioned2017-04-29T21:46:06Z
dc.date.available2017-04-29T21:46:06Z
dc.date.available2020-07-03T13:47:15Z
dc.date.issued2017-04-07
dc.identifier.urihttp://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija148300263737447.pdf?controlNumber=(BISIS)104087&fileName=148300263737447.pdf&id=7154&source=NaRDuS&language=srsr
dc.identifier.urihttps://nardus.mpn.gov.rs/handle/123456789/7980
dc.identifier.urihttp://www.cris.uns.ac.rs/record.jsf?recordId=104087&source=NaRDuS&language=srsr
dc.identifier.urihttp://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije14830026583754.pdf?controlNumber=(BISIS)104087&fileName=14830026583754.pdf&id=7155&source=NaRDuS&language=srsr
dc.description.abstractU disertaciji je ostvarena sineza amida i oksazolina žučnih kiselina, kao i njihovih alkil i alkilidenskih derivata polazeći od holne kiseline. Ipitano je ponašanje različitih okso derivata žučnih kiselina u uslovima Grignard-ove i Wittig-ove reakcije. Ispitana je biološka aktivnost odabranih sintetizovanih jedinjenjasr
dc.description.abstractSynhesis of bile acid amide and oxazoline derivatives, and their alkyl and alkylidene derivatives was accomplished starting from cholic acid. Also, chemical behavior of different bile acid oxo derivatives in Grignard and Wittig reaction was investigated. Biological activity  of selected synthesized compounds was evaluated.en
dc.languagesr (latin script)
dc.publisherУниверзитет у Новом Саду, Природно-математички факултетsr
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172021/RS//
dc.rightsopenAccessen
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceУниверзитет у Новом Садуsr
dc.subjectŽučne kiselinesr
dc.subjectBile aciden
dc.subjectalkyl derivativesen
dc.subjectGrignard reactionen
dc.subjectWittig reactionen
dc.subjectamidesen
dc.subjectoxazolinesen
dc.subjectantitumor activityen
dc.subjectantimicrobial activityen
dc.subjectalkil derivatisr
dc.subjectGrignard-ova reakcijasr
dc.subjectWittig-ova reakcijasr
dc.subjectamidisr
dc.subjectoksazolinisr
dc.subjectantitumorskaaktivnostsr
dc.subjectantimikrobna aktivnostsr
dc.titleSinteza i biološka ispitivanja novih derivata žučnih kiselinasr
dc.title.alternativeSynthesis and biological evaluation of new bile acid derivativesen
dc.typedoctoralThesisen
dc.rights.licenseBY-NC-ND
dcterms.abstractСакач, Марија; Марков, Синиша; Поша, Михаљ; Попсавин, Мирјана; Сакач, Марија; Чанади, Јанош; Бједов, Срђан; Синтеза и биолошка испитивања нових деривата жучних киселина; Синтеза и биолошка испитивања нових деривата жучних киселина;
dc.identifier.fulltexthttp://nardus.mpn.gov.rs/bitstream/id/39118/IzvestajKomisije8396.pdf
dc.identifier.fulltexthttp://nardus.mpn.gov.rs/bitstream/id/39117/Disertacija8396.pdf
dc.identifier.fulltexthttps://nardus.mpn.gov.rs/bitstream/id/39118/IzvestajKomisije8396.pdf
dc.identifier.fulltexthttps://nardus.mpn.gov.rs/bitstream/id/39117/Disertacija8396.pdf
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_nardus_7980


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