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Odgovor alveolo-kapilarne membrane na kontinuiranu fizičku aktivnost kod vrhunskih sportista sa različitom adaptacijom respiratornog sistema

Alveolo-capillary membrane response on continuous physical activity in elite athletes with various adaptations of the respiratory system

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Author
Lazović-Popović, Biljana R.
Mentor
Žugić, Vladimir
Committee members
Milenković, Branislava
Šipetić-Grujičić, Sandra
Kopitović, Ivan
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Abstract
Uvod: Difuzijski kapacitet pluća za ugljen monoksid (DLCO ili transfer faktor) definiše se kao količina gasa ugljen monoksida (CO) koja prolazi kroz alveolokapilarnu membranu tokom jednog minuta pri razlici pritiska od 1 kPa. DLCO zavisi od difuzijskog kapaciteta alveolarne membrane, krvnog volumena u alveolarnim kapilarama i brzini vezivanja CO sa oksihemoglobinom. Sposobnost respiratornog sistema da izvrši ovu razmenu određena je strukturnim i funkcionalnim svojstvima samih pluća. Ranije studije su pokazale da intenzivna, dugotrajna fizička aktivnost kod sportista dovodi po povećanja DLCO. Ciljevi istraživanja: U ovom radu ciljevi istraživanja bili su: da se ispita uticaj redovne, programirane i kontrolisane specifične fizičke aktivnosti na odgovor alveolokapilarne membrane u miru, kod sportista i zdravih ljudi, razlika u disajnim volumenima između fizički aktivnih (sportista) i neaktivnih, zdravih ljudi u miru i uticaj antropometrijskih parametara na njih i DLCO, a potom da se ispit...a uticaj intenziteta i učestalosti treninga na disajne volumene i difuzijski kapacitet. Dobijeni rezultati su poređeni sa rezultatima za opštu populaciju. Ispitanici i metode: Istraživanje je bazirano na dve studije: studija preseka i anamnestičku studiju. Istraživanjem je obuhvaćeno ukupno 157 ispitanika muškog pola, koji su prema obimu nedeljne fizičke aktivnosti podeljeni u dve grupe: fizički aktivne (vrhunske sportiste) i fizički neaktivne (kontrolne) ispitanike bez prisustva komorbiditeta. Grupu fizički aktivnih činilo je 115, a kontrolnu 42 ispitanika. Svi ispitanici su uvršteni u istraživanje konsekutivno. Grupu vrhunskih sportista činili su sportisti koji su se najmanje pet godina aktivno, takmičarski bavili različitom vrstom sporta, trenirali najmanje 10 sati nedeljno, a koji su prema vrsti sportske aktivnosti podeljeni u dve grupe: prva grupa- aerobna i druga- anaerobna grupa. Kontrolnu grupu činili su studenti muškog pola izabrani metodom slučajnog izbora po frekvenciji godišta kao u grupi sportista...

Introduction: The diffusion capacity of the lung for carbon monoxide (DLCO or transfer factor) is defined as the amount of gas of carbon monoxide (CO) passing through the alveolar-capillary membrane in the course of one minute at a pressure of 1 kPa. DLCO depends on the alveolar membrane diffusion capacity, the volume of blood in alveolar capillaries and the speed of the oxyhemoglobin binding CO. The capacity of the lung to exchange gas across the alveolarcapillary interface is determined by its structural and functional properties. Earlier studies have shown that intense, prolonged physical activity in athletes leads by increasing the DLCO. Aims: The aims of this study were: to investigate the effect of regular, programmed and controlled physical activity on a specific response alveolar-capillary membrane in the rest in athletes and sedentary controls, differences in respiratory volumes between physically active (athletes) and inactive, healthy people in peace and the impact of anthro...pometric parameters on them and DLCO, and then to examine the influence the intensity and frequency of training on lung volumes and diffusing capacity. Participants and methods: The research was based on two studies: crosssectional study and anamnestic study. The study included a total of 157 male respondents, who, according to the volume of weekly physical activity divided into two groups: physically active (top athletes) and physically inactive (control) examinees without the presence of comorbidity. Physically active group consisted of 115, and 42 control subjects. All subjects were included in the study consecutively. A group of elite athletes consisted of athletes who have at least five years of active competition practiced different kinds of sports, train at least 10 hours a week, and who, according to the type of sport activities are divided into two groups: aerobic and anaerobic. The control group consisted of male students selected randomly by frequency as in the age group athletes. After anthropometric measurements, all subjects underwent measurement of lung diffusion capacity for carbon monoxide (DLCO) using single breath method and spirometry testing...

Faculty:
Универзитет у Београду, Медицински факултет
Date:
26-09-2016
Keywords:
difuzijski kapacitet pluća / elite athletes / respiratorni sistem / vrhunski sportisti / vrsta sporta / lung diffusion capacity / respiratory system / type of sport
[ Google Scholar ]
Handle
https://hdl.handle.net/21.15107/rcub_nardus_7294
URI
https://nardus.mpn.gov.rs/handle/123456789/7294
http://eteze.bg.ac.rs/application/showtheses?thesesId=4262
https://fedorabg.bg.ac.rs/fedora/get/o:14006/bdef:Content/download
https://fedorabg.bg.ac.rs/fedora/get/o:14197/bdef:Izvestaj/download
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