Uticaj različitih materijala za definitivno punjenje kanala korena zuba na zarastanje koštanih defekata - eksperimentalna studija

Abstract

The aim of this study was to examine the influence of various materials used for the sealing of root canal system on healing of artificially prepared bone defects in the mandible of Wistar rats. In this experimental study, the following six materials for root canal obturation were examined within different time frames (15, 30, 60 and 90 days): Apexit, Endomethasone N, AH Plus, Roeko Seal, Fuji IX and Jodoform cement. The defects were filled with the previously mentioned materials in the experimental group while they were left to heal spontaneously in the control group. At the end of each time frame the animals were sacrificed and the preparations were analyzed by light microscopy. None of the examined materials caused any permanent or serious damage to the morphofunctional characteristics of bone tissue. Similar process of bone defect healing to that of the control group was observed in the defects filled with the materials Apexit, AH Plus, Roeko Seal, and Fuji IX, with the exception of Roeko Seal and Fuji IX which were not absorbed until the last observation period and AH Plus which was not absorbed until the sixtieth day. Slower healing process was observed in the group where Endomethasone N and Jodoform cement were used in comparison with the control group, here the healing process was followed by an inflammatory reaction which was present during longer observation periods as well. By the end of the last observation period (90 days) all the examined materials led to the healing of the treated bone defects.