Show simple item record

Synthesis, structure and properties of biodegradable aliphatic poly(ester ether)s.

dc.contributor.advisorĐonlagić, Jasna
dc.contributor.otherJeremić, Katarina
dc.contributor.otherNikolić, Marija
dc.contributor.otherPilić, Branka
dc.contributor.otherDunjić, Branko
dc.creatorStamenić, Dragana S.
dc.date.accessioned2016-08-27T16:05:38Z
dc.date.available2016-08-27T16:05:38Z
dc.date.available2020-07-03T09:24:18Z
dc.date.issued2014-07-03
dc.identifier.urihttp://eteze.bg.ac.rs/application/showtheses?thesesId=3705
dc.identifier.urihttps://nardus.mpn.gov.rs/handle/123456789/6369
dc.identifier.urihttps://fedorabg.bg.ac.rs/fedora/get/o:12520/bdef:Content/download
dc.identifier.urihttp://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=47570959
dc.description.abstractU ovom doktorskom radu su sintetisani i izuĉavani alifatski mulitblok poli(estar etri) sa ciljem da se razviju novi biodegradabilni polimerni materijali koji istovremeno poseduju elastomerna svojstva, kao i laku preradljivost koja je odlika termoplastiĉnih polimera. Elastiĉna svojstva potiĉu od dugaĉkih amorfnih mekih segmenta, dok kratki kristališući tvrdi segmenati obezbeĊuju polimeru odgovarajuću jaĉinu. Alifatski poliestri spadaju u grupu biodegradabilnih polimera koji su podloţni enzimskoj degradaciji ĉiji produkti razgradnje (dioli, kiseline i hidroksi kiseline) nisu toksiĉni i ulaze u metaboliĉke procese mikroorganizama. Biodegradabilnost zavisi od hemijske strukture, odnosa hidrofobnosti i hidrofilnosti, krutosti polimernih lanaca, kristalne strukture i stepena kristaliniĉnosti koji ima najveći uticaj na biodegradaciju. Biodegradabilna svojstva poliestara se mogu poboljšati povećanjem hidrofilnosti ugradnjom mekih hidrofilnih segmenata (npr. polietri) u polimerne lance. Biodegradabilni multiblok kopolimeri poli(estar etri) su sintetisani na bazi tvrdih poliestarskih segmenata poli(butilen sukcinata) (PBS), i dva razliĉita hidrofilna meka polietarska segmenta poli(etilen oksida) (PEO) i poli(tetrametilen oksida) (PTMO). Udeo mekih segmenata u kopolimerima je variran od 10 do 50 mas.%. Izuĉavan je uticaj razliĉitih mekih segmenata na strukturu, fiziĉke karakteristike, kao i na enzimsku i hidrolitiĉku degradaciju sintetisanih poli(estar etara). Poli(estar etri) su sintetisani dvostepenom reakcijom polikondenzacije u rastopu iz dimetil-sukcinata, 1,4-butandiola i polietara PEO (Mn=1000 g/mol) u prvoj seriji, odnosno PTMO (Mn=1000 g/mol) u drugoj seriji kopolimera, u prisustvu efikasnog katalizatora titan-tetrabutoksida (Ti(OC4H9)4) i bez dodatka termiĉkog stabilizatora. Struktura i sastav sintetisanih kopolimera, kao i proseĉna duţina tvrdih segmenata su odreĊeni 1 H NMR spektroskopijom. 1H NMR analizom je potvrĊena struktura sintetisanih kopolimera, a sastav poli(estar etara) je bio u dobrom slaganju sa sastavom polazne reakcione smeše. Vrednosti proseĉnog stepena polimerizacije tvrdih PBS segmenata u kopolimernim lancima ukazuju na smanjenje duţine tvrdih segmenata sa porastom udela inkorporiranih mekih polietarskih segmenata...sr
dc.description.abstractIn this dissertation were synthesized and studied aliphatic multiblock poly(ester ether)s with aim of developing biodegradable polymeric materials which also possess elastomeric properties and easy processability which is characteristic of thermoplastic polymers. Elastic behavior of these polymers originate from long amorphous soft segments, while short crystallizable hard segments provide great impact strength. Aliphatic polyesters belong to the group of biodegradable polymers susceptible to biological attack which products of biodegradation (diols, acids and hydroxy acids) are not toxic and are a part of the metabolic processes of microorganisms. Biodegradability depends on chemical structure, ratio of hydrophobicity to hydrophilicity, stiffness of the polymer chains, crystal structure and degree of crystallinity which has the greatest influence on degradation. The biodegradable properties of polyesters can be improved through increasing the hydrophilicity by the introduction of hydrophilic segments (e.g. polyethers) into the backbone of the polymer chains. Biodegradable multiblock poly(ester ether)s based on poly(butylene succinate) as the hard segment and two different hydrophilic polyethers soft segments poly(ethylene oxide) (PEO) in the first series, and poly(tetramethylene oxide) (PTMO) in the second series were synthesized. The content of soft segments was varied from 10 to 50 mass%. The effect of the introduction of different polyether soft segments on the structure, physical properties, as well as on enzymatic and hydrolytic degradation was investigated. The poly(ester ether)s were synthesized by two stage melt polycondensation reaction from dimethyl succinate, 1,4-butanediol and PEO (Mn =1000 g/mol) in the first series, and PTMO (Mn =1000 g/mol) in the second series in the presence of a highly effective catalyst, tetra-n-butyl-titanate (Ti(OBu)4) and without the addition of a heat stabilizer...en
dc.formatapplication/pdf
dc.languagesr
dc.publisherУниверзитет у Београду, Технолошко-металуршки факултетsr
dc.rightsopenAccessen
dc.sourceУниверзитет у Београдуsr
dc.subjectsegmentirani termoplastiĉni elastomerisr
dc.subjectsegmented thermoplastic elastomersen
dc.subjectpoly(ester ether)sen
dc.subjectcopolymer synthesisen
dc.subjectpoly(butylene succinate)en
dc.subjectpoly(ethylene oxide)en
dc.subjectpoly(tetramethylene oxide)en
dc.subjecthydrolytic degradationen
dc.subjectin vitro enzymatic degradationen
dc.subjectCandida rugosa lipaseen
dc.subjectpoli(estar etri)sr
dc.subjectsinteza kopolimerasr
dc.subjectpoli(butilen sukcinat)sr
dc.subjectpoli(etilen oksid)sr
dc.subjectpoli(tetrametilen oksid)sr
dc.subjecthidrolitiĉka degradacijasr
dc.subjectin vitro enzimska degradacijasr
dc.subjectCandida rugosa lipazasr
dc.titleSinteza, struktura i svojstva biodegradibilnih alifatskih poli(estar etara)sr
dc.titleSynthesis, structure and properties of biodegradable aliphatic poly(ester ether)s.en
dc.typedoctoralThesisen
dc.rights.licenseARR
dcterms.abstractЂонлагић, Јасна; Јеремић, Катарина; Николић, Марија; Пилић, Бранка; Дуњић, Бранко; Стаменић, Драгана С.; Синтеза, структура и својства биодеградибилних алифатских поли(естар етара); Синтеза, структура и својства биодеградибилних алифатских поли(естар етара);
dc.identifier.fulltexthttp://nardus.mpn.gov.rs/bitstream/id/18476/Disertacija4347.pdf
dc.identifier.fulltexthttps://nardus.mpn.gov.rs/bitstream/id/18476/Disertacija4347.pdf
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_nardus_6369


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record