Molekulski mehanizmi citotoksičnog delovanja trans-kompleksa platine(II) i platine(IV) sa piridinskim derivatima kao ligandima
Molecular mechanisms of the cytotoxicity of trans-platinum(II) and trans-platinum(IV) complexes with pyridine ligands
Author
Filipović, Lana M.Mentor
Korać, Aleksandra
Committee members
Aranđelović, SandraRadulović, Siniša
Tešić, Živoslav

Metadata
Show full item recordAbstract
Uvod: Hemioterapija koja se zasniva na platinskim agensima je ključna u lečenju
solidnih tumora, a jedan od vodeći itostatika koji se koristi je isplatina. Međutim, i
pored visoke efikasnosti cisplatine, toksičnost i razvoj rezistentnosti ograničili su nje (...)
Introduction: Platinum-based anticancer chemotherapy constitutes a cornerstone for the
treatment of various solid tumors. Cisplatin was one of the first chemotherapeutic
agents to exhibit broad efficacy and it remains among the most widely used agents in
t (...)
Faculty:
Универзитет у Београду, Биолошки факултетDate:
18-06-2014Projects:
- Pharmacodynamic and pharmacogenomic research of new drugs in the treatment of solid tumors (RS-41026)
- Structure-properties relationships of natural and synthetic molecules and their metal complexes (RS-172017)