Uticaj medikamentne terapije benigne hiperplazije prostate na seksualni život, funkciju i simptome donjeg urinarnog trakta
The impact of medical treatment of benign prostatic hyperplasia on sexual life, function and lower urinary tract symptoms
Doktorand
Stojanović, Nebojša A.Mentor
Ignjatović, IvanČlanovi komisije
Đorđević, NebojšaStojanović, Miroslav
Bašić, Dragoslav
Aleksić, Predrag
Metapodaci
Prikaz svih podataka o disertacijiSažetak
Introduction. Benign prostatic hyperplasia (BPH) causes disorders of voiding and sexual
function. Pharmacologic therapy reduces symptoms of voiding thus impacting sexual
function.
Objective. Determining sex life status in men with BPH before and after pharmacologic
treatment adapted to achieve satisfactory sexual function, and the impact this treatment on
the function and lower urinary tract symptoms.
Methods. 156 sexually active patients not previously treated for BPH were studied. After
clinical examinations, symptoms of voiding, sexual and ejaculatory function were measured
using standardized IPSS, IIEF and MSHQ-EjD questionnaires. After obtaining patients’
opinion about the importance of their sex life, the therapy was chosen and possible side
effects explained. Four groups each of 39 respondents were formed. One group used alphablockers,
tamsulosin, the second 5-alpha reductase inhibitor, finasteride, the third was
administered combination therapy and the fourth control group with...out therapy. The
complete examination procedure was repeated after 3 and 6 months of therapy.
Results. The mean age of patients was 61.16 2.97. In the therapy groups 87% reported their
sex life was important to some degree. Satisfaction with their sex life was reported by 47% of
patients before treatment and 67% 6 months after treatment. Questionnaire indicated general
improvement of sexual function (IIEF) in all groups statistically significant compared to
baseline only in the group on alpha-blockers (2.95 7.81; p=0.028). Overall satisfaction with
sex life compared to the beginning of treatment is significantly improved only in the group
with combined therapy.
Conclusion. Before treatment BHP, should be evaluated sexual function. Customize therapy
to patient’s expectations. Present side effects of drugs, especially to those emphasizing the
importance of sex life in order to improve it.