Prediktori koronarne bolesti kod bolesnika sa reumatoidnim artritisom, primarnim Sjögren sindromom, sistemskom sklerozom i sistemskim eritemskim lupusom
Predictors of coronary artery disease in patients with rheumatoid arthritis, primary Sjogren syndrome, systemic sclerosis and systemic lupus erhytematosus
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Kardiovaskularne bolesti (KVB) predstavljaju vodeći uzrok mortaliteta u svetu i najčešći vid komorbiditeta kod bolesnika sa sistemskim eritemskim lupusom (SLE), primarnim Sjögrenovim sindromom (SjS), sistemskom sklerozom (SSc) i reumatoidnim artritisom (RA). Hronična inflamacija u reumatskim bolestima može uticati na ubrzani razvoj KVB. Iako su faktori rizika za razvoj KVB u opštoj populaciji detaljno ispitivani i danas dobro poznati, kod pacijenata sa hroničnim reumatskim bolestima do sada nisu precizirani specifični faktori rizika za razvoj KVB, kao i njihova veza sa tradicionalnim faktorima rizika, čime bi se objasnila povećana incidenca KVB kod ovih bolesnika...
Introduction: Cardiovascular diseases (CVD) are the leading cause of death in the world and the most common type of comorbidity in patients with systemic lupus erythematosus (SLE), primary Sjögren's syndrome (SjS), systemic sclerosis (SSc), and rheumatoid arthritis (RA). Chronic inflammation in systemic rheumatic diseases can contribute to the development of CVD. Although risk factors for the CVD in the general population are well known, in patients with chronic rheumatic diseases risk factors for the CVD have not been specified as well as their connection with traditional risk factors, which would explain the increased incidence of CVD in these patients...