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Standardization of Montgomery-Asberg scale on a sample of depressed patients in Serbia

dc.contributor.advisorMihajlović, Goran
dc.contributor.otherIgnjatović Ristić, Dragana
dc.contributor.otherHinić, Darko
dc.contributor.otherMiljević, Čedo
dc.creatorVojvodić, Petar
dc.date.accessioned2021-04-19T09:37:35Z
dc.date.available2021-04-19T09:37:35Z
dc.date.issued2020-12-24
dc.identifier.urihttp://eteze.kg.ac.rs/application/showtheses?thesesId=7932
dc.identifier.urihttps://fedorakg.kg.ac.rs/fedora/get/o:1326/bdef:Content/download
dc.identifier.urihttps://nardus.mpn.gov.rs/handle/123456789/18244
dc.descriptionApstrakt: Depresija je psihijatrijski poremećaj koji karakterišu osećanja tuge, bezvoljnosti, neadekvatnosti i krivice, praćena nedostatkom energije, poremećajima apetita i spavanja, uključujući i nemogućnost doživljavanja zadovoljstva, kao i ideje o samoubistvu ili samopovređivanju. Skale za procenu depresije predstavljaju ključnu dopunu dijagnostici. U našoj zemlji koriste se brojne skale, ali nema publikovanih rezultata o normama primenjenih skala na našoj populaciji. Ciljevi ovog istraživanja bili su: standardizacija Montgomeri-Ašberg skale za procenu depresivnosti (MADRS), na kliničkoj i nekliničkoj populaciji u Srbiji, poređenje rezultata i konvergencija sa Hamiltonovom skalom za procenu depresivnosti (HAMD), kao i potvrđivanje prediktivne validnosti MADRS instrumenta. Uzorak ispitanika bio je konsekutivnog tipa i obuhvatao je grupaciju iz opšte i grupaciju iz kliničke populacije, a ispitana su 272 ispitanika, u dva navrata. Svim ispitanicima zadati su navedeni testovi, a uzorku iz opšte populacije dat je i BPRS (eng. Brief Psychiatric Rating Scale), čime je utvrđeno da kod ispitanika nije prisutan neki od mentalnih poremećaja. Utvrđeno je da skala MADRS ima odlične psihometrijske karakteristike, da je podjednako validna kao i HAMD, kao i da je njena diskriminativna validnost adekvatna. Test-retest analiza pokazala je da je skala pouzdana u vremenu. Utvrđena je i visoka pozitivna korelacija između dveju navedenih skala. Na kraju, ustanovljene su statistički značajne razlike između grupa u pogledu pola, starosti i obrazovanja za obe skale, ali su efekti utvrđenih razlika mali, te bi se mogli smatrati zanemarljivim. Glavni rezultat ovog istraživanja je standardizovana MADRS skala koja se pokazala odgovarajućom merom za rutinske, kliničke procene pojedinaca sa depresijom. Ispostavilo se da bi ova mera mogla da pruži pouzdane i validne procene težine depresije i da je moguće razlikovati klinički značajno poboljšanje od greške merenja sa velikom izvesnošću.sr
dc.descriptionAbstract: Depression is a psychiatric disorder characterized by feelings of sadness, lethargy, inadequacy, and guilt, accompanied by a lack of energy, appetite, and sleep disorders, including the inability to experience pleasure and the idea of suicide or self-harm. Depression assessment scales are a key complement to the diagnosis. Numerous scales are used in our country, but there are no published results on the norms of the scales applied to our population. The objectives of this study were: standardization of the Montgomery-Asberg Depression Rating Scale (MADRS) on the clinical and non-clinical population in Serbia, comparison of results, and convergence with the Hamilton Depression Rating Scale (HAMD), as well as confirmation of the predictive validity of the MADRS instrument. The sample of subjects was of the consecutive type and included a group from the general and a group from the clinical population, and 272 subjects were examined on two occasions. All subjects were tested using MADRS and HAMD, and a sample from the general population was also tested with BPRS (Brief Psychiatric Rating Scale), which determined that the subjects did not have any of the mental disorders. It was determined that the MADRS scale has excellent psychometric characteristics, it is equally valid as HAMD, and that its discriminant validity is adequate. The test-retest analysis showed that the scale was reliable over time. A strong positive correlation was also found between the two mentioned scales. Finally, statistically significant differences were found between groups in terms of gender, age, and education for both scales, but the effects of the identified differences were small and could be considered negligible. The main result of this study is a standardized MADRS scale that has been shown to be an appropriate measure for routine clinical assessments of individuals with depression. It turned out that this measure could provide reliable and valid estimates of the severity of depression and that it is possible to distinguish clinically significant improvement from measurement error with great certaintyen
dc.formatapplication/pdf
dc.languagesr
dc.publisherУниверзитет у Крагујевцу, Факултет медицинских наукаsr
dc.rightsopenAccessen
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceУниверзитет у Крагујевцуsr
dc.titleStandardizacija Montgomeri-Ašberg skale na uzorku depresivnih pacijenata u Srbijisr
dc.title.alternativeStandardization of Montgomery-Asberg scale on a sample of depressed patients in Serbiaen
dc.typePhD thesis
dc.rights.licenseBY
dc.identifier.fulltexthttp://nardus.mpn.gov.rs/bitstream/id/70989/Izvestaj_Petar_Vojvodic_Medicina.pdf
dc.identifier.fulltexthttp://nardus.mpn.gov.rs/bitstream/id/70988/Disertacija.pdf
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_nardus_18244


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