Vrste tribusa Scandicae (Apiaceae Lindley 1836, subfam. Apioideae) potencijalni izvor biološki i farmakološki aktivnih sekundarnih biomolekula

Abstract

Ispitani su hemijski sastav i biološka aktivnost šest samoniklih vrsta iz tribusa Scandiceae (familija Apiaceae): Anthriscus sylvestris, Anthriscus cerefolium, Chaerophyllum bulbosum, Chaerophyllum hirsutum, Chaerophyllum temulentum i Scandix pecten-veneris. LC-MS-MS analizom ekstrakata identifikovano je više desetina sekundarnih biomolekula iz klasa flavonoida, fenilpropenskih kiselina, lignana i kumarina. GC-MS analiza pružila je uvid u sastav volatilnih komponenti i njihov hemosistematski značaj. Potvrđeno je da sve ispitivane vrste imaju umereno antioksidantno, antiinflamatorno i antiproliferativno dejstvo.

Chemical composition and biological activity of six wild-growing species from Scandiceae tribe (Apiaceae family) – Anthriscus sylvestris, Anthriscus cerefolium, Chaerophyllum bulbosum, Chaerophyllum hirsutum, Chaerophyllum temulentum and Scandix pecten-veneris – was examined. By LC-MS-MS analysis, a large number of secondary biomolecules was identified in extracts, including flavonoids, phenylpropenic acids, lignans and coumarins. GC-MS analysis provided insight into volatile components composition and chemosystematic significance. All investigated species exhibited moderate antioxidant, anti-inflammatory and antiproliferative activity.