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Proteinski inženjering ligninolitičkih peroksidaza u cilju unapređenja degradacije tekstilnih boja

Improvement of ligninolytic peroxidases catalyzed textile dyes degradation by protein engineering

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2020
Disertacija.pdf (4.325Mb)
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Author
Ilić Đurđić, Karla Ž.
Mentor
Prodanović, Radivoje
Committee members
Ćirković Veličković, Tanja
Gavrović-Jankulović, Marija
Metadata
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Abstract
Tekstilna industrija iskoristi preko petsto hiljada tona boja godišnje. Neefikasnost procesa bojenja dovodi do otpuštanja izuzetno velikih količina tekstilnih boja u životnu sredinu. Kako je veliki broj studija pokazao da su sintetičke boje, a prevashodno azo boje izuzetno toksične i da predstavljaju pretnju za javno zdravlje njihovo uklanjanje iz životne sredine i otpadnih voda je od velikog značaja. Međutim, kako su sintetičke boje vrlo heterogeni molekuli koji u svojoj strukturi sadrže više funkcionalnih grupa veoma mali broj enzima ima mogućnost da katalizuje degradaciju širokog spektra ovih jedinjenja.
Textile industry spends over five hundred tons of dyes each year. Inefficiency of dying process releases high amounts of textile dyes to environment. As many synthetic dyes, especially azo dyes are proven to be toxic and represent a risk for public health, their removal from ecosystems and wastewaters is of great importance. However, synthetic dyes are very heterogeneous group of molecules with many different functional groups. Therefore, very few enzymes are able to catalyze their degradation.
Faculty:
Универзитет у Београду, Хемијски факултет
Date:
03-12-2020
Projects:
  • Allergens, antibodies, enzymes and small physiologically important molecules: design, structure, function and relevance (RS-172049)
Keywords:
Versatilna peroksidaza / Versatile peroxidase / lignin peroxidase / FACS / oxidative stability / saturation mutagenesis / catalytic triptophan / dyes degradation / lignin peroksidaza / FACS / oksidativna stabilnost / saturaciona mutageneza / katalitički triptofan / degradacija boja
[ Google Scholar ]
Handle
https://hdl.handle.net/21.15107/rcub_nardus_17770
URI
http://eteze.bg.ac.rs/application/showtheses?thesesId=7851
https://fedorabg.bg.ac.rs/fedora/get/o:23142/bdef:Content/download
http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=30770697
https://nardus.mpn.gov.rs/handle/123456789/17770

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