National Repository of Dissertations in Serbia
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrilic)
    • Serbian (Latin)
  • Login
View Item 
  •   NaRDuS home
  • Универзитет у Београду
  • Хемијски факултет
  • View Item
  •   NaRDuS home
  • Универзитет у Београду
  • Хемијски факултет
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Dekarbonilativno bromovanje i dekabronilovanje aromatičnih i heteoaromatičnih aldehida

Decarbonylative bromination and decarbonylation of aromatic and heteroaromatic aldehydes

Thumbnail
2019
Disertacija.pdf (8.263Mb)
IzvestajKomisije23268.pdf (288.1Kb)
Author
Ajdačić, Vladimir
Mentor
Opsenica, Igor
Committee members
Šolaja, Bogdan
Zlatović, Mario
Vulović, Bojan Z.
Gođevac, Dejan
Metadata
Show full item record
Abstract
Sintetisan je i okarakterisan katalizator magnetnih osobina na bazi paladijuma (Pd/Fe2O3) kao i katalizator na bazi paladijuma gde je kao nosač upotrebljena bakterijska nanoceluloza (Pd/BNC) i ispitana je njihova primena u reakciji dekarbonilovanja aldehida. Optimizovani reakcioni uslovi primenjeni su na aromatičnim i heteroaromatičnim aldehidima i na alifatičnim aldehidima koji imaju vodonikove atome na α- i δ-ugljenikovim atomima. Istovremeno, određen je mehanizam reakcije dekarbonilovanja i ispitana je mogućnost reciklovanja katalizatora. Pored reakcije dekarbonilovanja sintetisani katalizator Pd/Fe2O3 upotrebljen je i u reakciji reduktivnog dehalogenovanja arilhalogenida. U nastavku istražena je i reakcije dekarbonilativnog bromovanja 5-ariltiofen-2-karbaldehida. Eksperimentalnim i računarskim metodama ispitan je mehanizam reakcije kao i njena primena u sintezi triarilsupstituisanih tiofena.
Palladium-based catalysts obtained by palladium immobilization on maghemite (Pd/ γ-Fe2O3) and bacterial nanocellulose (Pd/BNC) as solid supports were synthesized and characterized and their application in the decarbonylation reaction was investigated. Optimized reaction conditions were applied to a series of aromatic and heteroaromatic aldehydes as well as to several aldehydes having alpha and beta hydrogen atoms. The mechanism of the mentioned transformation as well as the possibility of catalyst recycling has also been investigated. In addition to the decarbonylation reaction, the synthesized catalyst Pd/γ-Fe2O3 was used in the reductive dehalogenation reaction of arylhalides. The decarbonylative bromination reaction of 5-arylthiophene-2-carbaldehydes was also investigated. By combining experimental and computational methods, the mechanism of this reaction was examined, as well as its application to the synthesis of triaryl-substituted thiophene derivatives.
Faculty:
Универзитет у Београду, Хемијски факултет
Date:
08-11-2019
Projects:
  • The synthesis of aminoquinoline-based antimalarials and botulinum neurotoxin A inhibitors (RS-172008)
Keywords:
dekarbonilovanje / decarbonylation / dehalogenation / decarbonylative bromination / palladium / catalysis / dehalogenovanje / dekarbonilativno bromovanje / paladijum / kataliza
[ Google Scholar ]
Handle
https://hdl.handle.net/21.15107/rcub_nardus_17444
URI
http://eteze.bg.ac.rs/application/showtheses?thesesId=7600
https://fedorabg.bg.ac.rs/fedora/get/o:22540/bdef:Content/download
http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=51816719
https://nardus.mpn.gov.rs/handle/123456789/17444

DSpace software copyright © 2002-2015  DuraSpace
About NaRDus | Contact us

OpenAIRERCUBRODOSTEMPUS
 

 

Browse

All of DSpaceUniversities & FacultiesAuthorsMentorCommittee membersSubjectsThis CollectionAuthorsMentorCommittee membersSubjects

DSpace software copyright © 2002-2015  DuraSpace
About NaRDus | Contact us

OpenAIRERCUBRODOSTEMPUS